Biological activities of hydrazones include antibacterial, anticonvulsant, analgesic, anti-inflammatory, cardio protective, antiplatelet, anticancer etc., With proper designing, synthesis and structure activity relationship, a number of compounds can be developed with diverse biological activities. Eur J Med Chem. 2009; 44:3760–4. 49
Volume 2020, Issue 7. February 21, 2020. Volume 2020, Issue 6. February 14, 2020. Volume 2020, Issue 5. February 7, 2020. Volume 2020, Issue 4. January 31, 2020 Journal of Medicinal Chemistry Journal of Medicinal Chemistry will be publishing a Special Issue titled “Artificial Intelligence in Drug Discovery” in June 2020 with Guest Editors Jürgen Bajorath (University of Bonn), Steve Kearns (Google Research, Applied Science Team), and Patrick Walters (Relay Therapeutics). List of issues Journal of Enzyme Inhibition and Medicinal ... Browse the list of issues and latest articles from Journal of Enzyme Inhibition and Medicinal Chemistry. Log in | Register Cart. Search in: Journal Journal of Enzyme Inhibition and Medicinal Chemistry Submit Volume 24 2009 Volume 23 2008 Volume 22 2007 Volume 21 2006 Volume 20 2005 Volume 19 2004 Volume 18 2003 Volume 17 2002 Volume 16 2001 Synthesis of some novel N4-(naphtha[1,2-d]thiazol-2-yl ...
Improving Solubility via Structural Modification ... Jan 19, 2014 · J Med Chem 49:6672–6682 CrossRef Google Scholar 64. Zhang L, Zhu H, Mathiowetz A, Gao H et al (2011) Deep understanding of structure–solubility relationship for a diverse set of organic compounds using matched molecular pairs. 2,4-Disubstituted thiazoles as multitargated bioactive ... Jul 02, 2016 · Thiazoles are important heterocyclics exhibiting boundaryless biological activities, such as antibacterial, antifungal, anti-inflammatory, antitumor, antitubercular, antidiabetic, antiviral, and antioxidant. Substituents on a particular position of the thiazole ring affect the biological outcomes to a great extent. Therefore, researchers have synthesized compounds containing the thiazole ring Privileged s-triazines: structure and pharmacological ...
European Journal of Medicinal Chemistry - Elsevier The European Journal of Medicinal Chemistry is a global journal that publishes studies on all aspects of medicinal chemistry. It provides a medium for publication of original papers and also welcomes critical review papers. A typical paper would report on the organic synthesis, characterization and pharmacological evaluation of compounds. European Journal of Medicinal Chemistry (2009),44, 3350–3355 1 CiteSeerX - Document Details (Isaac Councill, Lee Giles, Pradeep Teregowda): Abstract: A series of imidazole based compounds were synthesized by reacting simple imidazoles either with alkyl halides in presence of tetrabutylammonium bromide (TBAB) or by conjugate addition of imidazoles to ethyl acrylate or glycosyl olefinic ester. The synthesized compounds were screened against M. tuberculosis European Journal of Organic Chemistry - Wiley Online Library Apr 23, 2020 · The European Journal of Organic Chemistry publishes Full Papers, Communications, and Minireviews from the entire spectrum of synthetic organic, bioorganic and physical-organic chemistry. It is published on behalf of Chemistry Europe, an association of 16 European chemical societies.. EurJOC receives great support from its international Editorial and Advisory Boards.
The estrogen receptors, ERα and ERβ, are important pharmaceutical targets. To develop ERβ-selective ligands, we synthesized a series of nonsteroidal compounds having a phenyl-2H-indazole core with different groups at C-3. Several of these show high affinity and good ERβ selectivity, especially those with polar and/or polarizable substituents at this site (halogen, CF3, nitrile); the best
Biological activities of hydrazones include antibacterial, anticonvulsant, analgesic, anti-inflammatory, cardio protective, antiplatelet, anticancer etc., With proper designing, synthesis and structure activity relationship, a number of compounds can be developed with diverse biological activities. Eur J Med Chem. 2009; 44:3760–4. 49 Synthesis, antimicrobial and cytotoxic activities of 1,3,4 ... Padmavathi V(1), Sudhakar Reddy G, Padmaja A, Kondaiah P, Ali-Shazia. Author information: (1)Department of Chemistry, Sri Venkateswara University, Tirupati 517 502, Andhra Pradesh, India. A new class of 1,3,4-oxadiazoles were prepared from acid hydrazides on treatment with … Benzisoxazole: a privileged scaffold for medicinal chemistry Nov 01, 2017 · The benzisoxazole analogs represent one of the privileged structures in medicinal chemistry and there has been an increasing number of studies on benzisoxazole-containing compounds. The unique benzisoxazole scaffold also exhibits an impressive potential European Journal of Pharmacology - Elsevier The European Journal of Pharmacology publishes research papers covering all aspects of experimental pharmacology with focus on the mechanism of action of structurally identified compounds affecting biological systems. The scope includes: Behavioural pharmacology. Neuropharmacology and …
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